Experimental infection of wild boars (Sus scrofa) with Rickettsia rickettsii and evaluation of the transmission potential to Amblyomma sculptum ticks.

Background: Brazilian spotted fever is a tick-borne disease caused by the bacterium Rickettsia rickettsii, whose main vector in Brazil is the tick Amblyomma sculptum. Amplifying hosts are essential for the perpetuation of this bacterium in the tick population as they can be sources of infection during bacteremic periods. Recent studies demonstrated the ability of suids (Sus scrofa) to sustain populations of A.

Real-world psoriasis treatment patterns and disease burden in Germany, with a focus on biologics and apremilast: data from a German statutory health insurance database.

Background: Psoriasis is a chronic, systemic, inflammatory skin disease, with increasing prevalence; however, few studies have reported real-world prescription patterns and healthcare burden.

Objectives: This retrospective, observational cohort study used statutory health insurance claims data (January 2014-December 2019) to estimate prevalence/incidence of moderate-to-severe psoriasis in Germany. Patient characteristics, treatment patterns/compliance, and healthcare resource utilization (HCRU)/costs were evaluated, focusing on apremilast and anti-interleukin (IL), and anti-tumor necrosis factor (TNF) biologics.

Comparative Genome Analysis of Canine Isolates.

: The One Health approach is crucial for managing and controlling the spread of antimicrobial resistance. is a recently identified bacterial species that seems to be a component of the oral microbiota of dogs; however, its pathogenic nature is questionable. : In this study, the antibacterial susceptibility of isolates was determined using the disk diffusion and broth microdilution methods.

Eco-epidemiological analysis of Rickettsia parkeri in domestic dogs and Amblyomma ovale ticks in the Atlantic rainforest of Northeast Brazil.

In Brazil, spotted fever (SF) is caused by two species of Rickettsia, both of which are transmitted by Amblyomma ticks: Rickettsia rickettsii, which results in severe and often fatal cases, and Rickettsia parkeri, which causes a mild illness. This study focused on R. parkeri in Amblyomma ovale ticks from the Maciço de Baturité region, Ceará, Northeast Brazil, an area endemic for SF with mild symptoms.