Publications by authors named "A B Liborio"

Article Synopsis
  • Study explores the impact of primary glomerulopathy on critically ill patients in the ICU, finding that infections and cardiovascular issues are common admission causes and sepsis is prevalent among these patients.
  • Among 307 patients analyzed, hospital mortality rates were similar to controls, but long-term mortality was high at 29% three years after ICU discharge, with reduced urine output and serum albumin levels being key predictors.
  • Findings indicate unique characteristics of this patient group, stressing the need for thorough risk assessment, while an unexpected lack of association between acute kidney injury and mortality warrants further investigation.
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Background: Continuous kidney replacement therapy (CKRT) is a crucial intervention for hemodynamically unstable patients with acute kidney injury (AKI). Despite the recommendations to offer a CKRT dose of 20-25 mL/kg/h, the optimal CKRT dose remains uncertain, especially whether low-dose CKRT is associated with poor outcomes. This study investigated the association between low CKRT dosage and 90-day mortality using a marginal structural model (MSM).

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Introduction: Cognitive decline is prevalent in maintenance hemodialysis patients. The blood-brain barrier has been implicated in cognitive decline. In this prospective cohort study, we investigated the associations between endothelium-related biomarkers and steeper cognitive decline in this population.

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Introduction: The current definition of acute kidney injury (AKI) includes increased serum creatinine (sCr) concentration and decreased urinary output (UO). Recent studies suggest that the standard UO threshold of 0.5 ml/kg/h may be suboptimal.

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