Publications by authors named "A B Lansdown"
Background: Hip replacement surgery can be painful; postoperative analgesia is crucial for comfort and to facilitate recovery. Regional anaesthesia can reduce pain and postoperative opioid requirements. The role of ultrasound-guided suprainguinal fascia iliaca block for analgesia after elective total hip arthroplasty is not well defined.
View Article and Find Full Text PDFBackground: Thyroid testing strategies vary across laboratories. First-line combined thyroid stimulating hormone (TSH) and freeT4 (FT4) have historically been preferred by many laboratories as this detects individuals with undiagnosed central hypothyroidism who can be missed with a first-line TSH-only strategy. However, an up-to-date evaluation of the utility of this approach is lacking.
View Article and Find Full Text PDFArticle Synopsis
- The study aims to improve the understanding of non-functioning pituitary microadenomas (micro-NFPAs) and their natural progression to inform patient care.
- Conducted across 23 endocrine departments in the UK, it analyzed clinical data from 459 patients over a median of 3.5 years, assessing tumor growth and hormonal changes.
- Results indicate a low probability of tumor growth (7.8% at 3 years) and rare development of hypopituitarism, suggesting that follow-up MRIs every 3 years and less frequent hormonal checks are adequate for managing micro-NFPAs.
Article Synopsis
- Thyroid hormones are essential for health and their levels change with age, which current reference intervals may not account for, leading to potential misdiagnoses.
- Evidence shows that TSH levels are highest at the beginning and end of life, while FT3 levels decline with age, affecting health outcomes differently in various age groups.
- There is a need for further research to establish appropriate thyroid hormone reference ranges that consider age-related variations to improve treatment and risk management strategies across all age demographics.