Publications by authors named "A B Insanov"

Sixty-seven patients with bronchial asthma treated with the bronchodilator insanovin for 4 weeks were followed up. The efficiency of aerosol therapy with insanovin as the basic agent was determined by the time course of changes in the clinical manifestations of the disease, in external respiratory functional and immunological parameters. In patients with first-degree bronchial obstruction, 2 weeks of aerosol therapy were sufficient to normalize the clinical manifestations of the diseases and external respiratory functional and immunological parameters.

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The parameters of humoral and cellular immunity were studied in patients with meningitis due to tuberculosis and other diseases. Peripheral blood and spinal fluid were measured in 91 and 76 patients with tuberculous meningitis, in 75 and 59 with purulent meningitis, and in 54 and 33 with serous meningitis, respectively. Comparing assessment of the findings revealed profound changes in the content of T lymphocytes and their subpopulations.

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The wide medical application of new highly active antituberculous agents (ATA) having a definite mechanism of action on immunological homeostasis makes pharmacological regulation of immunological responses real in patients with pulmonary tuberculosis. The purpose of this study was to examine the effect of major ATA on the body's immunological responsiveness in vitro, i.e.

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To assess the prognostic value of neutrophilic chemiluminescence, an examination was made of 68 patients with chronic bronchitis, 96 with bronchial asthma, and 34 apparently healthy individuals. Metabolic activity was determined by spontaneous and induced chemiluminescence in the whole blood and neutrophilic samples (the procedure being given). Patients with chronic bronchitis or bronchial asthma were found to have much higher metabolic activity in the neutrophils.

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An examination was made of 133 children and 89 adults, aged 3 to 60 years, who had admitted for suspected tuberculous meningitis. The diagnosis of tuberculous meningitis was established in 113 children and 79 adults. In the remaining 20 ill children and 10 adult patients, tuberculous etiology of the disease was rejected.

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