Publications by authors named "A B Gonzalez Escobar"
Background: Primary tic disorders (TD) are common movement disorders in childhood. However, it is unclear if international guidelines are applied in Latin America.
Objectives: To investigate the applicability of TD guidelines in Latin America.
IL-1β enhances susceptibility to atrial fibrillation in mice by acting through resident macrophages and promoting caspase-1 expression.
Nat Cardiovasc Res
February 2025
Atrial fibrillation (AF) is more prevalent in patients with elevated interleukin (IL)-1β levels. Here we show that daily administration of IL-1β for 15 days sensitizes mice to AF, leading to fibrosis, accumulation of β-pleated sheet proteins in the left atrium, and systemic inflammation, resembling the pathophysiological changes observed in patients with AF. IL-1β administration creates a positive feedback loop, dependent on the IL-1 receptor (IL-1R) activity in cardiac resident macrophages.
View Article and Find Full Text PDFIntroduction: Systemic lupus erythematosus (SLE) predominantly affects women, especially during their reproductive years, leading to increased risks during pregnancy. Latina women develop SLE at a younger age, which increases their susceptibility to pregnancy complications such as pre-eclampsia, preterm birth and fetal growth restriction.
Objective: The purpose of this study is to systematically review maternal and fetal outcomes in pregnant Latina women with SLE and to perform a meta-analysis to assess specific risks associated with the disease.
Article Synopsis
- The study investigates how to optimize the crystallization process of magnetic particles using a 2D system under an oscillating magnetic field.
- By adjusting the magnetic field's magnitude, researchers control the effective temperature, allowing the system to transition from fluid-like behavior to a crystalline state as the temperature decreases.
- Switching from linear cooling to a staggered cooling approach significantly reduces the time taken for particles to reach their lowest energy state, thus optimizing the crystallization time.
Article Synopsis
- Early integration of palliative care (PC) in inpatient oncology significantly improved patient outcomes, shifting more decedents to receive both inpatient and outpatient PC.
- The implementation of a criteria-based PC consultation model resulted in earlier consultations and a reduced need for intensive care and hospitalizations in the last month of life.
- Overall, this approach led to longer hospice stays and more deaths occurring at home, indicating a less aggressive end-of-life care strategy.