Publications by authors named "A B Clemmons"

Article Synopsis
  • - The study aimed to compare the efficacy and safety of two doses of melphalan (standard dose 200 mg/m² vs. reduced dose 140 mg/m²) for patients with multiple myeloma undergoing autologous stem cell transplantation, due to the lack of standard criteria for dose reduction.
  • - A total of 322 patients were reviewed, showing no significant differences in progression-free survival (PFS) and overall survival (OS) between the two dosing groups, regardless of age or kidney function.
  • - The findings suggest that reducing the dose of melphalan does not impact safety or efficacy, indicating the need for larger randomized trials to further investigate these results.
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Objective: To examine the impact of a critical care pharmacy elective (CCPE) on student performance in other courses in the Doctor of Pharmacy curriculum that emphasize clinical reasoning and decision making.

Methods: This is a retrospective, cohort study including all students from the 2019-2021 graduating classes enrolled in required courses, Pharmacotherapy and Integrated Patient Cases (IPCs). Students were divided for comparison based on completion of the CCPE.

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Recent literature demonstrates support for using methicillin-resistant (MRSA) nasal swab polymerase chain reaction (NaPCR) screening as an antimicrobial stewardship tool aiding early de-escalation of anti-MRSA antimicrobials. However, immunocompromised patients have been underrepresented in previous studies despite increased risk of morbidity and mortality from multidrug-resistant organisms (MDRO). The purpose of this study was to determine the negative predictive value (NPV) of the MRSA NaPCR in hospitalized, immunocompromised adult patients with suspected pneumonia.

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Chemotherapeutic agents and radiation therapy are associated with numerous potential adverse events (AEs). Many of these common AEs, namely chemotherapy- or radiation-induced nausea and vomiting, hypersensitivity reactions, and edema, can lead to deleterious outcomes (such as treatment nonadherence or cessation, or poor clinical outcomes) if not prevented appropriately. The occurrence and severity of these AEs can be prevented with the correct prescribing of prophylactic medications, often called "premedications.

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Introduction: To describe the impact of the SARS-CoV-2 pandemic on teaching, research, practice, and work-life integration for pharmacy faculty at research-intensive institutions.

Methods: An online survey related to transition to remote work, impact on faculty responsibilities, demographics, and other elements was sent to nine research-intensive United States public schools/colleges of pharmacy. Respondents were asked to describe challenges in moving to remote instruction as a result of the pandemic.

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