Publications by authors named "A B Cintra"
Background And Objectives: Computational fluid dynamics has advanced our knowledge of the pathogenesis of intracranial aneurysms and the dynamic changes observed after treatment. Herein, we analyze hemodynamic changes throughout the intervention stages for ruptured posterior communicating artery (PComA) aneurysms, treated with acute coiling and delayed flow diversion (FD).
Methods: We performed a retrospective analysis of ruptured PComA aneurysms treated with the acute coiling and delayed FD strategy between June 2013 to November 2022, using 3-dimensional reconstructions of digital subtraction angiographies.
Disintegrins are a class of peptides found in snake venom that inhibit the activity of integrins, which are essential cell adhesion receptors in tumor progression and development. In this work, moojecin, a RGD disintegrin, was isolated from Bothrops moojeni snake venom, and its antitumor potential in acute myeloid leukemia (AML) HL-60 and THP-1 cells was characterized. The isolation was performed using a C reverse-phase column in two chromatographic steps, and its molecular mass is 7417.
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- Mosquitoes are known to spread diseases like malaria, dengue, and Zika, prompting the search for innovative control methods beyond traditional insecticides.
- Research is uncovering various microorganisms that could effectively manage mosquito populations and their ability to transmit these diseases, but successful application depends on understanding the complex interactions between these microorganisms, mosquitoes, pathogens, and their environment.
- Despite significant scientific progress in identifying potential biocontrol agents and their mechanisms, few have been developed into practical products, indicating a need for more investment in research and biotech development for effective mosquito control solutions.
Background: The incidence of breast cancer is increasing globally; however, survival outcomes vary and are lower in developing countries.
Methods: We analyzed the 5- and 10-year survival rates for breast cancer according to the type of healthcare insurance (public . private) in a referral center for cancer care in the Brazilian southeast region.
Background: According to the Resolutions of the Collegiate Board of Directors RDC No. 20/2014, 214/2018, and 707/2022, validation of the temperature of thermal boxes for the transport of biological samples must be based on standardized procedures and tested by the Tissue Banks, guaranteeing safety and quality. Therefore, they can be simulated.
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