Publications by authors named "A Aw"
Protein language models have demonstrated remarkable performance in predicting the effects of missense variants but DNA language models have not yet shown a competitive edge for complex genomes such as that of humans. This limitation is particularly evident when dealing with the vast complexity of noncoding regions that comprise approximately 98% of the human genome. To tackle this challenge, we introduce GPN-MSA (genomic pretrained network with multiple-sequence alignment), a framework that leverages whole-genome alignments across multiple species while taking only a few hours to train.
View Article and Find Full Text PDFIntroduction: Laparoscopic ventral hernia mesh repair (LVHR) is gaining popularity possibly due to reduced complications, reduced hospital stay, early return to work and better cosmesis. In intra-peritoneal onlay method (IPOM) a dual layer composite mesh with an absorbable barrier on the visceral surface is used for minimising bowel adhesions. Three most popular prosthetic mesh scaffolds are polypropylene (PP), polyester and expanded polytetrafluoroethylene (ePTFE).
View Article and Find Full Text PDFPurpose: To assess the Gaiha Prio Retino +™Artificial Intelligence (AI) software for detecting diabetic retinopathy (DR).
Methods: This prospective study was conducted from March 1, 2021 to September 30, 2022 in the Ophthalmology department of the Abass NDAO Hospital (Dakar, Senegal). The clinical classification of DR was based on American Academy of Ophthalmology's.
Article Synopsis
- The review highlights the growing field of teledermatology research but notes significant gaps and variable depth in the evidence, which can inform clinicians and guide future research.* -
- Conducted according to established guidelines, the analysis included 14 systematic reviews from various databases, focusing on their characteristics, conditions studied, and the quality of the evidence.* -
- Findings indicate that teledermatology is generally comparable to traditional clinic dermatology and is well-received by patients, although issues like privacy, communication, and longer consultation times for healthcare professionals were noted.*
Article Synopsis
- - The study aimed to analyze how myelin oligodendrocyte glycoprotein-associated antibody disease (MOGAD) affects employment among adults internationally by measuring job loss, hours worked, and wages.
- - Researchers gathered data from 117 adults diagnosed with MOGAD across 13 countries, finding a decline in employment from 63.2% before diagnosis to 48.7% after, and a drop in average work hours from 31.6 to 19.5 hours per week.
- - Results showed that living in a high-income country was linked to better employment outcomes post-MOGAD, while factors like depressed mood and pain were associated with increased unemployment and reduced work hours.