Publications by authors named "A Audemard-Verger"
Article Synopsis
- * It typically affects Caucasians equally across genders and can also be associated with other autoimmune diseases like polyarteritis nodosa.
- * While ocular symptoms often have a good prognosis with potential recovery of vision, cochleo-vestibular issues can lead to serious and irreversible hearing loss, and treatment options are not well-established due to the condition's rarity.
Iron Boosts Antitumor Type 1 T-cell Responses and Anti-PD1 Immunotherapy.
Cancer Immunol Res
September 2024
Article Synopsis
- Cancers evade the immune system, and effective immunotherapies, especially those targeting PD1, work by enhancing T-cell functions, particularly IFNγ production.
- While immunotherapies have improved patient outcomes, not everyone responds, necessitating alternative treatments to enhance their effectiveness.
- The study shows that iron supplementation boosts T-cell responses and enhances the effectiveness of anti-PD1 therapy in mice, indicating that combining iron with immunotherapy could improve cancer treatment outcomes.
Introduction: IgA vasculitis diagnosis relies primarily on clinical features and is confirmed by pathological findings. To date, there is no reliable noninvasive diagnostic biomarker.
Objective: We aimed to explore the baseline serum metabolome of adult patients with IgA vasculitis to identify potential diagnostic biomarkers.
Introduction: McArdle disease, or glycogen storage disease type V (GSD 5), is a rare metabolic myopathy linked to an autosomal recessive myophosphorylase deficiency.
Case Report: We report the case of a 17-year-old male patient who was referred to the emergency department for the management of acute inflammatory low back pain, without traumatic context, associated with an increase of CK at 66,336 UI/L (N<192UI/L) and a CRP at 202mg/L. The immunological assessment was negative and the spinal MRI showed images in favor of necrotizing fasciitis affecting the erector spinae muscles, among others.