Publications by authors named "A Aubouy"

Introduction: Innate immunity is crucial to reducing parasite burden and contributing to survival in severe malaria. Monocytes are key actors in the innate response and, like macrophages, are plastic cells whose function and phenotype are regulated by the signals from the microenvironment. In the context of cerebral malaria (CM), monocyte response constitutes an important issue to understand.

View Article and Find Full Text PDF

The composition of essential oils varies according to culture conditions and climate, which induces a need for simple and inexpensive characterization methods close to the place of extraction. This appears particularly important for developing countries. Herein, we develop an analytical strategy to determine the thymol content in Ocimum Gratissimum, a medicinal plant from Benin.

View Article and Find Full Text PDF
Article Synopsis
  • Cerebral malaria (CM) is a severe and deadly form of malaria affecting children in Africa, with mechanisms of neuroinflammation and patient outcomes still not fully understood.* -
  • The study involved 70 children with CM in southern Benin, assessing various clinical and biochemical markers to determine the factors influencing survival versus death.* -
  • Key findings indicated that children who died from CM had elevated plasma levels of inflammatory markers like TNF and IL-1β, as well as decreased levels of urinary PGEM, suggesting these biomarkers could help predict mortality risk in CM patients.*
View Article and Find Full Text PDF

Cerebral malaria (CM) is one of the most severe forms of malaria and is a neuropathology that can lead to death. Monocytes have been shown to accumulate in the brain microvasculature at the onset of neurological symptoms during CM. Monocytes have a remarkable ability to adapt their function to their microenvironment from pro-inflammatory to resolving activities.

View Article and Find Full Text PDF

This work presents 4 open source potentiostat solutions for performing accurate measurements in cyclic voltammetry and square wave voltammetry at a low price. A very simple and easy to reproduce analogic board (c.a.

View Article and Find Full Text PDF