Publications by authors named "A Astruc"

Background: The global increase in caesarean sections (CS), currently at 21.1% of all deliveries, has led to a rise in uterine scar defects, or 'niches', at the hysterotomy site. These niches, detectable in 13%-84% of cases via transvaginal ultrasound (TVS) and 42%-84% through sonohysterography (SHG), may contribute to gynaecological complications, including abnormal uterine bleeding, chronic pain and secondary infertility.

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  • The study aimed to assess how common intrauterine synechiae (scar tissue) are after women undergo medically-treated postpartum hemorrhage (PPH) and how different treatment methods might influence this condition.
  • Conducted at Angers University Hospital, the study involved 83 women who experienced PPH, with diagnostic hysteroscopy performed 12 weeks after delivery to check for synechiae.
  • Findings showed that 24% of participants had mild synechiae, with second manual uterine examinations and bimanual massage identified as key risk factors, indicating a need for more research on the long-term effects of these complications.
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  • - Cervical ectopic pregnancy is a rare condition, making up less than 1% of all ectopic pregnancies, and the case highlighted involves a successfully managed instance at 9 weeks gestation.
  • - The management involved minimally invasive techniques, including uterine artery embolization and the administration of methotrexate, with no complications observed during follow-up.
  • - After treatment, the patient's β-hCG levels normalized by Day 104, and the uterine cavity fully recovered within 6 months, along with a literature review on cervical ectopic pregnancy.
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  • Uterine innervation is crucial to female reproductive health and has significant implications for conditions like endometriosis; recent histological advances have revealed its complex structure and role in these disorders.
  • This review summarizes current research on uterine innervation, focusing on its effects on endometriosis and associated pain, using a systematic approach to analyze relevant studies.
  • The review identified 45 studies that highlighted a trend towards increased nerve fiber density in ectopic endometrial tissue, suggesting a link between this heightened innervation and the chronic pain seen in endometriosis patients.
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Colorectal cancer is the third most common cancer in France, and the second regarding mortality with almost 17,100 deaths each year. When screened at an early stage, the five-year survival is around 90 %. Since 2008, a screening program has been introduced in France with the fecal occult blood test.

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