Publications by authors named "A Aseffa"
Background: Clinically diagnosed pulmonary tuberculosis (TB) (CDPTB) patients account for a huge proportion of TB. However, little is known about the genetic diversity and drug resistance profile of Complex (MTBC) strains in this group of patients.
Method: Unmatched case-control study was conducted among 313 PTB patients to compare the genetic diversity of MTBC and their drug resistance profiles among CDPTB ( = 173) and bacteriologically confirmed pulmonary TB (BCPTB) ( = 140) patients.
Article Synopsis
- Healthcare in low- and middle-income countries is facing challenges due to the rise of multidrug-resistant bacteria, leading to increased illness and death.
- A study conducted in Ethiopia identified 74 bacterial isolates from sepsis patients across four hospitals, revealing significant antimicrobial resistance and clonal patterns among the bacteria.
- Findings highlight the urgency for enhanced infection control measures and improved use of antibiotics, as well as adopting advanced techniques for bacterial identification to combat these emerging threats.
Article Synopsis
- The study explores the prevalence of multidrug-resistant Pantoea species among sepsis patients in Ethiopia, highlighting the growing burden of sepsis caused by these pathogens.
- Conducted from October 2019 to September 2020, researchers analyzed blood cultures from 1,416 patients across four hospitals, identifying various Pantoea species and characterizing them through advanced genomic techniques.
- Findings revealed that P. dispersa was the most common, displaying genetic similarities and known antimicrobial resistance genes, emphasizing the need for improved infection control measures to combat these resistant strains.
Objectives: As post kala-azar Dermal Leishmaniasis (PKDL) threatens the success of the Visceral Leishmaniasis (VL) elimination initiative, we aimed to investigate the PKDL burden, including an active search for PKDL in leprosy-negative skin lesion cases. We also investigated their health-seeking behavior and perceived level of stigma.
Methods: This was a cross-sectional survey among inhabitants in the VL-endemic villages of the five most VL-endemic upazilas.