Publications by authors named "A Aruanno"
SonoVue (Bracco, Milan, Italy) is a drug used in ultrasonography for the purpose of increasing the echogenicity of blood or fluids by improving the signal-to-noise ratio. : We described a case of anaphylaxis due to SonoVue and performed a literature review. : We reported a case of anaphylaxis secondary to the administration of SonoVue and described all the 13 literature cases.
View Article and Find Full Text PDFImmediate hypersensitivity reactions (iHSRs) to taxanes are observed in 6% and 4% of gynecologic and breast cancer patients, respectively. Drug desensitization is the only option, as no comparable alternative therapy is available. Surfactants in the taxane formulation have been implicated in the immunopathogenesis of iHSRs, although sporadic skin test (ST) positivity and iHSRs to nab-paclitaxel have suggested the involvement of the taxane moiety and/or IgE-mediated pathomechanisms.
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- - Severe asthma affects roughly 10% of asthma patients and is marked by poor lung function and high eosinophil counts; this study aims to define asthma remission more clearly using a structured method.
- - A panel of experts developed and refined a questionnaire through a two-round Delphi method to evaluate consensus on criteria for asthma remission, including clinical and inflammatory aspects.
- - The analysis confirmed specific criteria for both complete and partial clinical remission, creating a practical tool to assess treatment effectiveness in patients with severe asthma enrolled in the Severe Asthma Network Italy registry.
International guidelines suggested skin tests with Polyethylene-glycol (PEG) and polysorbate 80 (PS-80), to investigate a possible hypersensitivity to these excipients either to identify subjects at risk of developing allergic reactions to Covid-19 vaccines, or in patients with suspected IgE mediated hypersensitivity reactions (HR) to the Covid-19 vaccine. The main purpose of this study was to investigate the prevalence of PEG and PS sensitization in patients with a clinical history of HR to drugs containing PEG/PS and in patients with a suspected Covid-19 vaccine immediate HR. This was a multicenter retrospective study conducted by allergists belonging to 20 Italian medical centers.
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