Publications by authors named "A Arrieta-Gisasola"

Article Synopsis
  • S. 4,[5],12:i:- is now the leading Salmonella strain in pigs, often linked to antibiotic and heavy metal resistance.
  • A study analyzed 78 strains from 1999-2021, discovering that 91.23% of S. 4,[5],12:i:- strains carried mobile genetic elements (MGEs) for resistance, while only 14.29% of S. Typhimurium did.
  • The evolution of resistance patterns shows a shift from certain MGEs to others, highlighting the impact of EU antibiotic bans and ongoing heavy metal use in animal production, stressing the need for effective interventions.
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Salmonella enterica subsp. enterica serovar Typhimurium variant 4,[5],12:i:- (so called S. 4,[5],12:i:-) has rapidly become one of the most prevalent serovars in humans in Europe, with clinical cases associated with foodborne from pork products.

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The emergence of foodborne strains carrying antimicrobial resistance (AMR) in mobile genetic elements (MGE) is a significant public health threat in a One Health context requiring continuous surveillance. Resistance to ciprofloxacin and cephalosporins is of particular concern. Since pigs are a relevant source of foodborne for human beings, we studied transmissible AMR genes and MGE in a collection of 83 strains showing 9 different serovars and 15 patterns of multidrug resistant (MDR) previously isolated from pigs raised in the conventional breeding system of Northern Spain.

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The use of whole-genome sequencing (WGS) for bacterial characterisation has increased substantially in the last decade. Its high throughput and decreasing cost have led to significant changes in outbreak investigations and surveillance of a wide variety of microbial pathogens. Despite the innumerable advantages of WGS, several drawbacks concerning data analysis and management, as well as a general lack of standardisation, hinder its integration in routine use.

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Extensive pig systems are gaining importance as quality production systems and as the standard for sustainable rural development and animal welfare. However, the effects of natural foods on epidemiology remain unknown. Herein, we assessed the presence of and the composition of the gut microbiota in pigs from both -free and high prevalence farms.

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