Publications by authors named "A Ariza"

Transcription and its regulation pose a major challenge for genome stability. The helicase RECQL5 has been proposed as an important factor to help safeguard the genome, and is the only member of the human RecQ helicase family that directly binds to RNA Polymerase II (Pol II) and affects its progression. RECQL5 mitigates transcription stress and genome instability in cells, yet the molecular mechanism underlying this phenomenon is unclear.

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  • Geometric optical illusions (GOIs) highlight mismatches between what we see and the actual physical stimuli, allowing researchers to explore how sensation and perception interact.
  • A study conducted with 30 adults revealed that different physical properties of GOIs have varying effects on perceptual biases, and these effects can interact in complex ways.
  • By combining psychophysics with computational modeling of the primary visual cortex, the researchers found that certain adjustments in neural parameters could replicate human perceptual biases, suggesting that different physical attributes work together to create a GOI and offering insights into the mechanisms behind perception.
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  • The Shock-CAT study aimed to assess in-hospital mortality and prognosis in cardiogenic shock (CS) patients, comparing those with acute myocardial infarction (AMI) to those without it.
  • Out of 382 patients studied, AMI-CS exhibited higher in-hospital mortality rates (37.1%) compared to non-AMI-CS (26.7%), with AMI-CS patients requiring more mechanical circulatory support.
  • The IABP-SHOCK II score was found to be more accurate than the CardShock score in predicting 90-day mortality for AMI-CS patients, while both scores performed similarly for non-AMI-CS patients.
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