Proton Pump Inhibitors for Inducing and Maintaining Remission in Eosinophilic Esophagitis: An Updated Systematic Review and Meta-Analysis.

Background & Aims: Proton pump inhibitor (PPI) therapy results in clinical and histological remission in approximately 50% of eosinophilic esophagitis (EoE) patients. We aimed to systematically update this topic due to cumulative data from pediatric/adult populations in wider geographical settings.

Methods: A search in MEDLINE, EMBASE, and SCOPUS databases was performed.

Impact of conservative versus conventional instrumentation on the release of inflammatory mediators and post-operative pain in mandibular molars with asymptomatic irreversible pulpitis: A randomized clinical trial.

Aim: This study aimed to compare the release of inflammatory mediators and post-operative pain after conservative and conventional root canal preparations of mandibular molars with asymptomatic irreversible pulpitis.

Methodology: Forty-five healthy patients diagnosed with asymptomatic irreversible pulpitis were randomly assigned to three groups based on the system used for root canal preparation (n = 15): ProTaper Gold, OneShape and TruNatomy. Gingival crevicular fluid samples were collected for baseline measurements, 24 and 72 h after root canal treatment.

Agri-food waste to phenolic compounds: Life cycle and eco-efficiency assessments.

The increase in the consumption of food products and the management of food waste have endangered the sustainability of the food sector. The need to move forward on the European bioeconomy requires to evaluate waste valorization strategies, to convert a non-valorized resource into a high-added value production in the market. In this regard, the focus of this research article is the valorization of orange peel and tomato seed wastes to produce bioactive compounds, such as carotenoids.

Case report: Central venous stenosis-induced intracranial hypertension.

Intracranial hypertension due to central venous stenosis (CVS) is an under-recognized but potentially morbid complication of central venous catheters that can have a benign course if recognized and treated early. Here we report a case of a 23-year-old woman requiring hemodialysis via right subclavian catheter who presented with an intracranial hypertension syndrome and sudden visual loss secondary to right innominate vein thrombosis that improved after angioplasty treatment. This case illustrates how CVS can alter the pressure gradient between the subarachnoid space and the cerebral venous sinuses by increasing venous pressure, affecting cerebrospinal fluid drainage.

Microplastic accumulation and histological effects on the Atlantic deep-sea scale-worm Laetmonice filicornis.

Small benthic scavengers and carnivores, such as polychaetes, are very interesting to assess the accumulation and transfer of microplastics (MPs) to higher trophic levels in marine ecosystems. In this study we evaluate the presence, accumulation and impacts of MPs in the North-Atlantic deep-sea polychaete Laetmonice filicornis. Three types of MPs were identified: fishing lines, fibres and fragments, mostly black in colour, followed by red and blue ones.