Objectives: Elderly hospitalized patients with inflammatory bowel disease (IBD) flare and concurrent Clostridioides difficile infection (CDI) are considered at high risk of IBD-related complications. We aimed to evaluate the short, intermediate, and long-term post-discharge complications among these patients.
Methods: A retrospective multicenter cohort study assessing outcomes of elderly individuals (≥60 years) hospitalized for an IBD flare who were tested for CDI (either positive or negative) and discharged.
Background: Few data are available addressing the impact of post-operative management of Crohn's disease (CD) on long-term clinical course.
Aim: To assess the evolution of post-operative management strategies over the last 40 years and their impact on the re-operation rate of CD.
Methods: We included 657 patients with CD who had undergone their first radical ileo-caecal resection between 1980 and 2020.
Background/aims: Endoscopic stenting for stricturing Crohn's disease (CD) is an emerging treatment that achieves more persistent dilatation of the stricture over time than endoscopic balloon dilatation (EBD). We aimed to explore the efficacy and safety of stenting for the treatment of CD strictures.
Methods: A systematic electronic literature search was performed (PROSPERO; no.
Background: The administration of biological drugs in inflammatory bowel diseases (IBD) is increasingly moving from intravenous to subcutaneous formulations.
Aims: To evaluate the efficacy and safety of vedolizumab subcutaneous administration after switching from intravenous administration in ulcerative colitis (UC) patients in corticosteroid-free clinical remission.
Methods: An observational, multicentre, prospective study was conducted by the Italian Group for the study of IBD (IG-IBD).