A Pelvic Mass in a Young Patient With Crohn's Disease.

Castleman disease (CD) is a rare group of lymphoproliferative disorders subdivided based on clinical features. Although not fully understood, the pathogenesis of both CD and Crohn's disease involves a combination of immune dysregulation and infectious and environmental factors. Interleukin-6, a proinflammatory cytokine, is associated with both diseases and can serve as a common therapeutic target in CD.

Assessment and improvement of the quality of radiotherapy treatment planning CT images using a clinically validated phantom based method and a multicentre intercomparison.

Purpose: To develop a phantom method of image quality assessment for radiotherapy planning CT protocols (head and neck (H&N) and prostate) and validate results against clinical image quality. Test with data from different scanners and suggest protocol adjustments.

Methods: Macros measured patient water-equivalent diameter and noise from clinical CT images.

Canadian Network for Mood and Anxiety Treatments 2024 Clinical Practice Guideline for the Management of Perinatal Mood, Anxiety, and Related Disorders: Guide de pratique 2024 du Canadian Network for Mood and Anxiety Treatments pour le traitement des troubles de l'humeur, des troubles anxieux et des troubles connexes périnatals.

Background: The Canadian Network for Mood and Anxiety Treatments (CANMAT) publishes clinical practice guidelines for mood and anxiety disorders. This CANMAT guideline aims to provide comprehensive clinical guidance for the pregnancy and postpartum (perinatal) management of mood, anxiety and related disorders.

Methods: CANMAT convened a core editorial group of interdisciplinary academic clinicians and persons with lived experience (PWLE), and 3 advisory panels of PWLE and perinatal health and perinatal mental health clinicians.