Prevalence of Dysphonia in Children: A Systematic Review and Meta-Analysis.

Objectives: To analyze the prevalence of pediatric voice disorders.

Study Design: Systematic review (SR) and meta-analysis.

Methods: The research question of this SR was "What is the prevalence of dysphonia in children?" An electronic search was performed using the Medical Literature Analysis and Retrieval System online (Medline), Literatura Latino-Americana e do Caribe em Ciências da Saúde, EMBASE, Web of Science, and SCOPUS database.

Recurring Giant Conjunctival Cyst Effectively Treated With 20% Trichloroacetic Acid.

Giant conjunctival cysts, though rare, can cause significant discomfort and functional impairment due to their size as well as their potential for rupture and recurrence. We report the case of a 51-year-old female who presented with a recurrent giant conjunctival cyst in her left eye, experiencing considerable discomfort and pain upon eye movement. The cyst, located in the left eye, had previously recurred after surgical excision, though visual acuity remained 20/20 bilaterally.

Association between Driving Pressure, Systemic Inflammation and Non-pulmonary Organ Dysfunction in Patients with Acute Respiratory Distress Syndrome, a Prospective Pathophysiological Study.

Background: Driving pressure is thought to determine the effect of low tidal ventilation on survival in patients with acute respiratory distress syndrome. The leading cause of mortality in these patients is non-pulmonary multiorgan dysfunction, which is believed to worsen due to the biological response to mechanical ventilation (biotrauma). Therefore, we aimed to analyze the association between driving pressure, biotrauma, and non-pulmonary multiorgan dysfunction.

Fecal microbiome alterations of mice following immunization with gold nanoparticle vaccines against enterohemorrhagic Escherichia coli.

Background: Enterohemorrhagic Escherichia coli (EHEC), a group of enteric pathogenic bacteria that is a major cause of human diarrheal disease, must interact with the diverse intestinal microbiome during colonization and subsequently overcome the environmental challenges to survive and cause disease. While this relationship, and how the microbiome modulates infection of EHEC, has been studied, it is less understood how the microbiome is impacted during treatment for an EHEC infection. One area that is notably lacking in knowledge is how vaccination can impact the intestinal microbiome composition, and therefore, influence vaccine efficacy.