Publications by authors named "A Anghel"

Background: Stroke is the third leading cause of disability. Virtual reality (VR) has shown promising results in post-stroke rehabilitation. The VR TRAVEE system was designed for the neuromotor rehabilitation of the upper limb after a stroke and offers the ability to track limb movements by providing auditory feedback and visual augmentation.

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Co-simulation can bring improvements to the development of cyber-physical perceptive systems (CPPS) in critical fields, allowing uninterrupted system operation and flexibility to use both real-time sensor data and non-real-time data. This paper proposes a co-simulation approach that integrates physical systems and communication systems, including both hardware and software components. This study demonstrates how systems of different natures with discrete or continuous events can be simulated using three methods: time stepped, global event driven, and variable stepped.

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  • Bupropion is an antidepressant used for major depressive disorder, seasonal affective disorder, and smoking cessation, but it can cause common side effects like nausea and insomnia, as well as delayed allergic reactions that may appear weeks after starting the medication.
  • A case study of a 27-year-old male showed significant improvement in depression on bupropion, but he developed itchiness and hives after 28 days, which resolved after switching to a different medication, venlafaxine.
  • There is limited awareness among clinicians about bupropion's potential for delayed hypersensitivity reactions, particularly affecting younger males and those with prior allergies.
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  • Gorlin-Goltz syndrome (GGS) is an autosomal dominant genetic condition linked to an increased risk of multiple basal cell carcinomas (BCCs) and associated with mutations in the PTCH1 or SUFU genes, though diagnosis can occur without these markers.
  • The main symptom of GGS is the development of multiple BCCs, which usually grow slowly and stay localized, but can sometimes be more aggressive in affected individuals.
  • A recent case demonstrates that radiation therapy (RT), typically avoided due to the heightened risk of BCCs in GGS patients, can be effective and safe in treating an inoperable BCC that had metastasized, suggesting the need for personalized treatment approaches.
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  • * Concerns about complications like bleeding during surgery remain, especially since von Willebrand factor (VWF), important for blood clotting, is affected in AS patients.
  • * This study tracked 39 AS patients undergoing valve replacements to explore how the type and size of the artificial valve influence post-surgery VWF levels, aiming to improve valve choice and patient care strategies.
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