Publications by authors named "A Angers-Loustau"

Article Synopsis
  • A new database aims to gather all publicly available information on the performance of CE-marked diagnostic medical devices (IVDs) and laboratory-developed devices for COVID-19 in one place.
  • This database is manually curated, regularly updated, and serves as a follow-up to the European Commission's guidelines from April 2020.
  • The database is freely accessible to the public at https://covid-19-diagnostics.jrc.ec.europa.eu/.
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Next Generation Sequencing technologies significantly impact the field of Antimicrobial Resistance (AMR) detection and monitoring, with immediate uses in diagnosis and risk assessment. For this application and in general, considerable challenges remain in demonstrating sufficient trust to act upon the meaningful information produced from raw data, partly because of the reliance on bioinformatics pipelines, which can produce different results and therefore lead to different interpretations. With the constant evolution of the field, it is difficult to identify, harmonise and recommend specific methods for large-scale implementations over time.

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Article Synopsis
  • The environmental impact of plastic waste is widely studied, but the effects of micro- and nanoplastics on human health, especially through food and drink, are not well understood.
  • Most research focuses on environmental contamination and lacks a consistent methodology, with many studies either examining wild animal impacts or lab experimentation on microplastic ingestion.
  • This review analyzes studies since 2010 about micro- and nanoplastics in over 200 animal species and food products, highlighting the need for standardized methods to accurately assess human exposure through diet.
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Gadoids are a group of fish with historical importance in the fishing industry. The high demand for cod is one of the reasons why cod products are often mislabelled, and numerous observations have been made on the replacement of Atlantic cod (Gadus morhua) by cheaper species or its illegal capture in contravention of fish quotas. Fish species identification is traditionally based on morphological features, but this may be difficult in case of heat-treated or processed products, or where the species look similar, as in the Gadoid group.

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Next-Generation Sequencing (NGS) technologies are expected to play a crucial role in the surveillance of infectious diseases, with their unprecedented capabilities for the characterisation of genetic information underlying the virulence and antimicrobial resistance (AMR) properties of microorganisms.  In the implementation of any novel technology for regulatory purposes, important considerations such as harmonisation, validation and quality assurance need to be addressed.  NGS technologies pose unique challenges in these regards, in part due to their reliance on bioinformatics for the processing and proper interpretation of the data produced.

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