We extend a previously developed epidemiological model for West Nile virus (WNV) infection in humans in Greece, employing laboratory-confirmed WNV cases and mosquito-specific characteristics of transmission, such as host selection and temperature-dependent transmission of the virus. Host selection was defined by bird host selection and human host selection, the latter accounting only for the fraction of humans that develop symptoms after the virus is acquired. To model the role of temperature on virus transmission, we considered five temperature intervals (≤ 19.
View Article and Find Full Text PDFIn this study, initial elements of a modelling framework aimed to become a spatial forecasting model for the transmission risk of West Nile virus (WNV) are presented. The model describes the dynamics of a WNV epidemic in population health states of mosquitoes, birds and humans and was applied to the case of Greece for the period 2010-2019. Calibration was performed with the available epidemiological data from the Hellenic Centre for Disease Control and Prevention and the environmental data from the European Union's earth observation program, Copernicus.
View Article and Find Full Text PDFBackground: The prognostic implication of mutant KRAS (mKRAS) among patients with primary disease in the rectum remains unknown.
Methods: From 2000 to 2018, patients undergoing hepatectomy for colorectal liver metastases at 10 collaborating international institutions with documented KRAS status were surveyed.
Results: A total of 834 (65.