Indian Traditional Treatments for Psoriasis: A Critical Appraisal of Available Evidence Supporting Efficacy.

Objective: To examine data from studies supporting the clinical efficacy of medical approaches from India traditional systems of medicines like Ayurveda, Unani, Siddha, and Homeopathy for psoriasis using outcome indicators employed in clinical practice and research.

Methods: Searches were conducted between December 2019 and September 2020 in databases PubMed, Scopus, Web of Science and Ovid Medline using search terms including traditional, complementary, psoriasis, Kushtha, Ayurveda, Siddha, Unani, Homeopathy and clinical. Controlled trials, case series and case reports published from India were included.

Siddha fasting in obese acute decompensated heart failure may improve hospital outcomes through empowerment and natural ketosis.

Background: Morbid obesity (BMI > 35 kg/m2 with comorbid conditions) is present in 25 - 35% of acute decompensated heart failure (AHF) patients. Prevalence of HF increases with duration of morbid obesity from 30% at 15 years to over 90% at 30 years. There is a need to develop pragmatic therapies that address the unique physical and mental challenges faced by obese AHF patients.

Repurposing Siddha mercurial drug for mild to moderate COVID-19 - Case series and exploration of its chemical profile.

(VKM) is a mercury-based traditional Siddha drug used to treat various types of fevers and inflammatory diseases. We report our experience of using VKM successfully in the treatment of 5 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected patients along with its chemical profile. A family comprising of 5 members, with age ranges between 13 and 77, both male and female, one with pre-existing renal impairment, SARS-CoV-2 positive with mild to moderate category were treated with VKM along with the specific dietary practice.

Vernonia cinerea regenerates tubular epithelial cells in cisplatin induced nephrotoxicity in cancer bearing mice without affecting antitumor activity.

Background: Traditional Siddha Medicine advises using metal-based formulations to treat cancers. In the case of any toxicities during the therapy, Siddha physicians use (VC) whole plant (crude aqueous extract-CAE) to reverse the toxic effects.

Aim: To evaluate the nephroprotective activity of CAE and its fractions in cisplatin-induced nephrotoxicity and to assess whether they compromise the anticancer efficacy of cisplatin.

Enhanced Monarchy Butterfly Optimization Technique for effective breast cancer diagnosis.

Breast cancer is the biggest curse for the women society in the world since the survival factor of the infected patients is ensured only when it is detected at the early localized stage. The majority of the intelligent schemes proposed for detecting the breast cancer relies on the human skill that helps in trustworthy determination of essential pattern that confirms the existence of the infected cancer cells for deciding upon the course of treatment. Further, most of the research works contributed in the literature for detecting breast cancer necessitates huge time and laborinvolved that increases the time of diagnosis.