Publications by authors named "A Amedei"
The advent of next-generation sequencing (NGS) technologies has made it possible to investigate microbial communities in various environments, including different sites within the human body. Therefore, the previously established belief of the sterile nature of several body sites, including human blood, has now been challenged. However, metagenomics investigation of areas with an anticipated low microbial biomass may be susceptible to misinterpretation.
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- Age-related macular degeneration (AMD) significantly affects vision in the elderly, and recent research suggests a link between gut health and its development.
- This study examined the impact of micronutrient supplementation, including lutein and saffron, on patients with neovascular AMD compared to those receiving standard anti-VEGF therapy alone.
- Results showed improvement in visual acuity and gut microbiota composition in patients taking the supplements, implying potential benefits of micronutrients in supporting eye health and balancing gut-related factors in AMD.
Non-communicable diseases (NCDs) are the leading cause of morbidity and mortality worldwide. These conditions have numerous health consequences and significantly impact patients' lifestyles. Effective long-term treatment is essential since NCDs are irreversible.
View Article and Find Full Text PDFUp to the last update, the gut microbiome (GM) had been associated with a different physiologic host process, including those affecting cardiovascular health. The carotid intima-media thickness (IMT) is an indicator of atherosclerosis and cardiovascular risk. The GM influence on atherosclerosis progression has garnered growing attention in recent years but the consensus in subclinical atherosclerosis remains elusive.
View Article and Find Full Text PDFCardiovascular diseases (CVDs), which comprise coronary heart disease, hypertension, and stroke, collectively represent the number one cause of death globally. Atherosclerosis is the dominant cause of CVDs, and its risk factors are elevated levels of low-density lipoprotein cholesterol and triglycerides, hypertension, cigarette smoking, obesity, and diabetes mellitus. In addition, diverse evidence highlights the role played by inflammation and clonal haematopoiesis, eventually leading to immunity involvement.
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