Publications by authors named "A Ambrosino"
There are still several viral infections affecting a considerable number of the world's population, causing thousands of deaths each year. There are no drugs available for most viral infections and for many not even a vaccine. The marine kingdom is characterized by a huge chemical diversity; however, there is currently on the market only one drug derived from the sea with antiviral properties, called Ara-A.
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- - Cancer is a significant global health issue, leading to ongoing research into effective treatments, particularly focusing on natural compounds from plants that may help in prevention and therapy due to their pharmacological benefits.
- - The review evaluates the therapeutic potential of five natural compounds—apigenin, quercetin, piperine, curcumin, and resveratrol—highlighting their anticancer mechanisms, roles in personalized cancer care, and advantages like low toxicity and compatibility with standard treatments.
- - It emphasizes the need for innovative delivery systems and personalized approaches to enhance the effectiveness of these compounds, ultimately supporting a multidisciplinary strategy for improving cancer management and patient outcomes.
The battle against the COVID-19 pandemic has spurred a heightened state of vigilance in global healthcare, leading to the proliferation of diverse sanitization methods. Among these approaches, germicidal lamps utilizing ultraviolet (UV) rays, particularly UV-C (wavelength ranging from 280 to 100 nm), have gained prominence for domestic use. These light-emitting diode (LED) lamps are designed to sanitize the air, objects, and surfaces.
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- The text discusses a case of an opportunistic yeast infection found in a lung cancer patient in Naples, highlighting the challenges for immunocompromised individuals in the Mediterranean region.
- It details the identification of the yeast through various methods such as Gram staining and MALDI-TOF MS, which are important for accurate diagnosis.
- The study emphasizes the significance of early microbiological diagnosis for effective treatment, revealing that 5-fluorocytosine is the most effective antifungal against the yeast, followed by other antifungals like itraconazole and voriconazole.
Mammals exhibit two distinct types of adipose depots: white adipose tissue (WAT) and brown adipose tissue (BAT). While WAT primarily functions as a site for energy storage, BAT serves as a thermogenic tissue that utilizes energy and glucose consumption to regulate core body temperature. Under specific stimuli such as exercise, cold exposure, and drug treatment, white adipocytes possess a remarkable ability to undergo transdifferentiation into brown-like cells known as beige adipocytes.
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