Publications by authors named "A Ambresin"
Importance: Some patients worldwide are asked to acquire an anti-vascular endothelial growth factor (anti-VEGF) agent from a pharmacy, store it, and then bring it to a physician for intravitreal injection (IVT). Anti-VEGF agents must be stored in the refrigerator to avoid bacterial contamination or denaturation. Some cases of severe intraocular inflammation have been reported following IVT of more recently approved anti-VEGF agents, which might be explained by thermal instability.
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- Diabetic macular edema (DME) is a serious vision impairment often treated with anti-VEGF agents, but some patients don't respond well; this study tests the effectiveness of the intravitreal dexamethasone (DEX) implant as a second-line option for those not responding adequately or facing high treatment burdens.
- Conducted across seven Swiss clinical sites, the retrospective study analyzed 95 eyes from patients who had previously received anti-VEGF therapy for at least six months before starting DEX treatment, focusing on visual acuity and retinal swelling.
- Results showed a significant reduction in anti-VEGF injections after DEX treatment and improvement in retinal thickness, with BCVA remaining stable, while some patients experienced side effects requiring additional
Purpose: To highlight the influence of preocular and ocular vascular circulatory dynamics on the vascular density (VD) of retinal capillary plexuses (RCPs) and choriocapillaris (CC) in patients with and without cardiovascular risk (CVR) factors.
Methods: A retrospective observational study in patients with and without CVR factors (type 1 and 2 diabetes, arterial hypertension, and hypercholesterolemia). Fluorescein (FA) and indocyanine (ICGA) angiography circulatory times were arterial time (FA), start (FA) and end (FA) of laminar flow, and arterial time (ICGA), respectively.
This article outlines the management of transgender and non-binary adolescents at CHUV. The current rise in visibility of this topic is associated with an increased demand for intervention and at the same time with an increased generation of continuously expanding medical evidence to guide interventions. The close collaboration among various specialized adolescent health services enables an interdisciplinary evaluation of diagnostic elements and indications for potential psychological, social or medical interventions.
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