Publications by authors named "A Ambreen"

Article Synopsis
  • - The study evaluated plasma levels of ferritin, C-reactive protein (CRP), and adenosine deaminase (ADA) as biomarkers for monitoring treatment response in patients with extrapulmonary tuberculosis (EPTB), specifically those with TB lymphadenitis and TB pleuritis.
  • - Measurements were taken from 92 patients at the beginning of treatment, and again at 2 and 6 months, showing that elevated baseline levels of all three biomarkers significantly decreased after treatment.
  • - Results indicated that a combination of the three biomarkers could predict treatment response with high accuracy, achieving 83% at 2 months and 100% at 6 months, highlighting their potential as indicators of treatment effectiveness.
View Article and Find Full Text PDF
Article Synopsis
  • Primary lymphoma is confined to the brain and central nervous system (CNS), while secondary lymphoma spreads to the CNS after affecting other body organs.
  • The prognosis is worse for patients with secondary CNS lymphoma compared to primary cases.
  • The text reports a case where secondary CNS lymphoma was misdiagnosed as a cerebral abscess due to its atypical characteristics, highlighting the importance of early diagnosis and treatment.
View Article and Find Full Text PDF
Article Synopsis
  • A study assessed plasma procalcitonin (PCT) levels in 48 patients with TB lymphadenitis and 41 with TB pleuritis, finding elevated levels in 89% of cases, with higher levels in TB lymphadenitis compared to pleuritis.
  • PCT levels showed a negative correlation with the severity of symptoms and certain inflammatory biomarkers, but were not related to the bacterial load in patients.
  • The elevated PCT levels did not decrease with anti-TB treatment, suggesting it might not be a reliable marker for monitoring treatment response, indicating a need for further research with more cases.
View Article and Find Full Text PDF
Article Synopsis
  • The study highlights the importance of assessing quality of life (QoL) in patients with extrapulmonary tuberculosis (TB), specifically focusing on those with tuberculous lymphadenitis and pleuritis.
  • Data was collected from 376 patients at different stages of treatment to evaluate various health domains related to their overall well-being.
  • Results showed that while most patients experienced QoL improvements post-treatment, some had recurrences, and factors like income and living conditions were found to negatively influence emotional health, indicating the need for healthcare providers to consider these non-medical factors.
View Article and Find Full Text PDF

Cardiomegaly is among the disorders categorized by a structural enlargement of the heart by any of the situations including pregnancy, resulting in damage to heart muscles and causing trouble in normal heart functioning. Cardiomegaly can be defined in terms of dilatation with an enlarged heart and decreased left or biventricular contraction. The genetic origin of cardiomegaly is becoming more evident due to extensive genomic research opening up new avenues to ensure the use of precision medicine.

View Article and Find Full Text PDF