Publications by authors named "A Aluffi"
Context: Liver transplantation (LT) is considered the ideal therapy for patients with hepatocellular carcinoma (HCC) having cirrhosis but the shortage of liver donors and the risk of dropout from the wait list due to tumor progression severely limit transplantation. A new prognostic score, the HCC-model for end-stage liver disease (HCC-MELD), was developed by combining α-fetoprotein (AFP), MELD, and tumor size, to improve risk stratification of dropout in patients with HCC.
Objectives: In this study, we investigated the ability of the HCC-MELD score in predicting the posttransplant for patients fulfilling Milan criteria (MC).
Article Synopsis
- Liver transplantation (LT) is the best treatment for liver cancer (HCC) patients with cirrhosis, but donor shortages and tumor progression make it challenging.
- A study analyzed 131 HCC patients who met the Milan Criteria, proposing a new prognostic score to better predict cancer recurrence after transplantation.
- The new model considers tumor size and grading, resulting in improved accuracy for predicting recurrence rates compared to the existing Milan Criteria.
We describe an unprecedented, disastrous complication after bilateral lung transplantation (BLT), a bilateral bronchial dehiscence with a right bronchoesophageal fistula leading to life-threatening septic shock. We also report the successful endoscopic management of this complication by double stenting and stress the efficacy of the multidisciplinary approach to this critical case.
View Article and Find Full Text PDFIntroduction: Use of extended criteria donors is one of the strategies to face the scarcity of donors for lung transplantation.
Methods: Between November 2002 and May 2009, we performed 52 LTs in 50 recipients, 10 of whom (group A) received lungs from donors aged 55 years or older (median, 58.5; range, 56-66 years) for comparison with 28 patients (group B) transplanted with lungs from donors younger than 55 years (median, 25.
The preliminary experience of the first Italian program of pediatric intestinal transplantation is presented herein. A multidisciplinary group with broad experience in pediatric solid organ transplantation started the program. Nine children with complications of chronic intestinal failure were listed for transplantation.
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