Publications by authors named "A Alperovitch"
Background and Purpose- Evidence links antidepressant use with cerebral small vessel disease; however, it remains unclear whether people with depression face comparable risk. This study aims to determine the association between antidepressant drug use and depression with markers of cerebral small vessel disease. Methods- One thousand nine hundred five participants (mean age, 72.
View Article and Find Full Text PDFIntroduction: Benzodiazepine use has been associated with increased risk of dementia. However, it remains unclear whether the risk relates to short or long half-life benzodiazepines and whether it extends to other psychotropic drugs.
Methods: Prospective cohort study among 8240 individuals ≥65, interviewed on medication use.
Objective: To determine whether the addition of data derived from magnetic resonance imaging (MRI) of the brain to a model incorporating conventional risk variables improves prediction of dementia over 10 years of follow-up.
Design: Population based cohort study of individuals aged ≥ 65.
Setting: The Dijon magnetic resonance imaging study cohort from the Three-City Study, France.
Objective: To determine the association between use of lipid lowering drugs (statin or fibrate) in older people with no known history of vascular events and long term risk of coronary heart disease and stroke
Design: Ongoing prospective population based cohort study recruited in 1999-2000, with five face-to-face examinations.
Setting: Random sample of community dwelling population aged 65 years and over, living in three French cities (Bordeaux, Dijon, Montpellier).
Participants: 7484 men and women (63%) with mean age 73.