Publications by authors named "A Alpan"
Article Synopsis
- - The study examined the effects of diosgenin (DG), a steroidal saponin, on alveolar bone loss in rats with induced periodontitis using imaging and tissue analysis methods.
- - Rats were divided into four groups, with two receiving different doses of DG over 29 days, and findings showed that as DG dosage increased, it effectively reduced periodontal damage and improved bone formation markers.
- - Results indicated that DG not only lowered the expression of detrimental proteins related to bone loss but also significantly decreased alveolar bone loss compared to the periodontitis group, suggesting its potential as a treatment for periodontal issues.
Articaine versus lidocaine inferior alveolar nerve block in posterior mandible implant surgeries: a randomized controlled trial.
Med Oral Patol Oral Cir Bucal
March 2023
Background: The aim of this study is to compare the effects of %4 articaine and %2 lidocaine on inferior alveolar nerve block (IANB) for implant surgery in the posterior mandible.
Material And Methods: The patients who have inserted implants in the posterior mandible were divided into 2 groups for IANB: lidocaine and articaine. VAS = visual analog scale, pain during surgery and injection, lip numbness time, mandibular canal-implant apex distance, age, gender, bone density, implant number, release incision, adjacent teeth, and duration of surgery were analyzed using t-test, Mann-Whitney U test, Spearman's coefficient, and, Pearson's chi-squared test.
Article Synopsis
- This study investigates the effects of topical treatments (hyaluronic acid, hypochlorous acid, and flurbiprofen) on healing after free gingival graft surgery in 60 patients.
- Patients were divided into four groups and monitored for 28 days, with healing assessed using various methods, including pain levels and tissue healing metrics.
- Results showed that hyaluronic acid significantly improved healing compared to the others, with less pain and faster epithelization, while hypochlorous acid and flurbiprofen were less effective in promoting wound healing.
A series of 4,4'-diimine/4,4'-diazobiphenyl derivatives were designed, synthesized, and evaluated for their ability to inhibit both the acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes, as well as Aβ aggregation, in vitro. The AChE and BChE inhibition assays demonstrated that all compounds displayed moderate AChE inhibitory activity in the range of IC = 5.77-16.
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