Publications by authors named "A Allieri-Rosenthal"
Flow cytometric analysis of peripheral blood neutrophil myeloperoxidase expression in myelodysplastic neoplasms (MPO-MDS-Valid): protocol for a multicentre diagnostic accuracy study.
Charlotte Planta Caroline Bret Delphine Manzoni Anne-Catherine Lhoumeau Caroline Mayeur Rousse Alessandra Allieri-Rosenthal
BMJ Open
June 2024
Article Synopsis
- A study is investigating whether flow cytometric analysis of myeloperoxidase expression in peripheral blood can accurately rule out myelodysplastic neoplasm (MDS), potentially reducing unnecessary bone marrow aspirations for about 35% of patients.
- The MPO-MDS-Valid project involves recruiting 400 patients from multiple hospitals in France to validate the testing method by comparing it to established diagnoses made by experienced hematopathologists.
- The research has been ethically approved, and results will be shared through publication to inform medical practice and improve patient care.
Unlabelled: Monitoring of body temperature, but also of C-reactive protein (CRP) level is performed in infected patients treated with antibiotics. These two parameters having low specificity for any diagnosis, our aim was to evaluate the usefulness of CRP in this context.
Patients And Method: A representative sample of patients was randomly extracted from our medical computerized tables.