Publications by authors named "A Alfarano"
Article Synopsis
- Inadequate lung fluid clearance is crucial in the development of transient tachypnea of the newborn (TTN), and the study aims to see if left ventricular diastolic dysfunction affects this process.
- The study involved 27 neonates with TTN compared to 27 controls, using echocardiography and lung ultrasounds to assess heart and lung function over different time periods after birth.
- Results showed that neonates with TTN had significantly lower left atrial strain reservoir (LASr) measurements, indicating diastolic dysfunction, which may hinder lung fluid clearance, suggesting that monitoring LASr could help predict the need for respiratory support.
Neonatologist Performed Echocardiography (NPE) is one of the emerging technologies used to evaluate Systemic Blood Flow (SBF) in term and preterm infants. Right Ventricular Output (RVO) can assess SBF correctly in the absence of significant interatrial or interventricular shunts, even in the presence of a large patent ductus arteriosus (PDA), but only few studies evaluated inter-observer variability in neonates. Furthermore, measuring pulmonary peak flow (PF) provides a simple screening tool for low SBF state, easier and faster to perform than RVO; no previous studies evaluated PF inter-observer variability.
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- - The study contrasts traditional app-based research methods by adopting a participant-centric approach that includes more intensive engagement through high-friction tasks and the use of wearable sensors to collect data on stress and health symptoms.
- - Conducted between May and November 2020 with 365 US frontline healthcare workers, the study demonstrated high retention and data adherence rates, with over 81% of participants completing the study over four months.
- - The findings suggest that building trust and offering support can enhance participant engagement in digital health studies, as evidenced by a high daily engagement with both the app and wearable technology.
Objectives: Previous studies suggest that otherwise healthy individuals who have a parental history of hypertension (PH+) have an accentuated reactive rise in catecholamines and cortisol to laboratory stressors as well as elevated plasma levels when compared with those with no parental history (PH-); however, few, if any, studies have evaluated whether parental history affects the responses of these hormones to changing environmental circumstances in everyday life. The purpose of this study was to compare urinary catecholamine (epinephrine and norepinephrine) and cortisol excretion and ambulatory blood pressures (BPs) across three daily microenvironments between women with and without a parental history of hypertension.
Methods: The women in the study (PH+, N = 62, age = 35.