The use of polymeric passive samplers (often polydimethylsiloxane, PDMS, or low-density polyethylene, LDPE) to indicate water concentrations of hydrophobic organic compounds under environmental conditions generally requires two key parameters, a compound-specific polymer-water equilibrium partition coefficient (K), and the degree of equilibration achieved in a given environmental exposure scenario. Herein, we have developed model to extrapolate equilibration of performance reference compounds between polymer and pore water across different compound classes that is also dependent upon accurate estimates of K. We have also developed quantitative structure-activity relationship (QSAR) models, to estimate K for PAHs, PCBs, DDx, and dioxin/furans for the two most common polymeric samplers, PDMS and LDPE.
View Article and Find Full Text PDFIntroduction: Brain neoplasms and central nervous system (CNS) disorders, particularly gliomas, have shown a notable increase in incidence over the last three decades, posing significant diagnostic and therapeutic challenges. MicroRNAs (miRNAs) have emerged as promising biomarkers due to their regulatory role in gene expression, offering potential enhancements in glioma diagnosis and prognosis.
Methods: This systematic review and meta-analysis, adhering to PRISMA guidelines, included 25 studies for diagnostic accuracy and 99 for prognostic analysis, published until August 27th, 2023.
Asian Pac J Cancer Prev
February 2024
Introduction: Breast cancer represents a formidable peril to the female populace on a worldwide level. The association between breast cancer and various factors, including viral infections, has been extensively investigated. Recently, the link between HBV infection and breast cancer patients has garnered attention.
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