Effectiveness of Occlusal Splints in the Management of Temporomandibular Disorders: Comparisons of Treatment Approaches and Digital Versus Conventional Fabrication Techniques.

This research explores the types and effectiveness of occlusal splints in managing temporomandibular disorders (TMDs). TMDs encompass a range of musculoskeletal and neuromuscular conditions affecting the jaw, causing pain, limited movement, and discomfort. Occlusal splints, also known as bite guards, are commonly used in dentistry to alleviate TMD symptoms by relaxing jaw muscles, preventing joint trauma, and protecting teeth.

Right Ventricular Free Wall Strain Predicts ATTR Prognosis as Well as Biomarker- Based Staging Systems.

Aims: The diagnosis of transthyretin amyloidosis (ATTR) significantly impacts the management and prognosis of patients initially presenting with heart failure (HF). Despite recent advances in treatment, prognosticating ATTR remains challenging. We aimed to assess echocardiographic parameters associated with mid-term prognosis in patients with wild-type ATTR using a biomarker staging system as a reference point.

Characterization of cardiac resynchronization therapy response through machine learning and personalized models.

Introduction: The characterization and selection of heart failure (HF) patients for cardiac resynchronization therapy (CRT) remain challenging, with around 30% non-responder rate despite following current guidelines. This study aims to propose a novel hybrid approach, integrating machine-learning and personalized models, to identify explainable phenogroups of HF patients and predict their CRT response.

Methods: The paper proposes the creation of a complete personalized model population based on preoperative CRT patient strain curves.

Does Laparoscopic Sleeve Gastrectomy lead to Barrett's esophagus, 5-year esophagogastroduodenoscopy findings: A retrospective cohort study.

Introduction: Laparoscopic Sleeve Gastrectomy (LSG) is one of the most prevalent approaches to tackle obesity and its co-morbidities. The main complication following the LSG is Gastro-esophageal reflux disease (GERD), with most patients developing worsening symptoms of GERD, and a small number progressing to Barrett's esophagus. This retrospective analysis aims to assess the rate of GERD pre- and post- LSG as well as the rate of progression to Barrett's.