Publications by authors named "A Al-Shami"

Article Synopsis
  • Bisphenol A (BPA) is an endocrine disruptor commonly found in plastics, which may impact mental health through alterations in key signaling pathways during early development.
  • A study on male rats exposed to BPA revealed changes in neurotransmitter levels and signaling molecules related to anxiety, depression, and cognitive functions from juvenile to adulthood.
  • The research highlights that BPA exposure in early life can have lasting negative effects on behavior and brain function by modifying the NMDAR/PSD-95-PTEN/AKT signaling pathway.
View Article and Find Full Text PDF

Thyroid hormones are essential for brain development, and a shortage throughout the fetal and postnatal periods can result in mood disorders. Perinatal exposure to bisphenol A (BPA) affects thyroid activity and dependent processes indirectly during pregnancy or early postnatal life. This is particularly important because it may cause changes in tissue ontogeny, increasing the risk of developing disorders later in life.

View Article and Find Full Text PDF

Zinc-Manganese spinel ferrites (ZnMnFeO) are nowadays very attractive magnetic materials for cancer diagnostic and therapy. With the help of intense ultrasonic waves, sonochemical synthesis method was used to prepare stoichiometric and chemically homogenous nanoparticles by varying the manganese content. The crystal structure along with the size and shape of the as-prepared nanoparticles were described using XRD, TEM and FT-IR techniques, while cations distribution was carefully investigated using XPS and Mössbauer spectroscopic techniques and supported with density functional theory calculations.

View Article and Find Full Text PDF

This work develops the first laser-induced graphene (LIG)-based electrochemical sensor with a superhydrophobic fluorous membrane for a flexible acetylcholine (ACh) sensor. ACh regulates several physiological functions, including synaptic transmission and glandular secretion. The ACh sensing membrane is doped with a fluorophilic cation-exchanger that can selectively measure ACh based on the inherent selectivity of the fluorous phase for hydrophobic ions, such as ACh.

View Article and Find Full Text PDF