Publications by authors named "A Al-Mohammad"
Is it just another case of vaccine-induced myocarditis? A case report and key insights.
Eur Heart J Case Rep
November 2024
Article Synopsis
- - The rising incidence of myopericarditis cases has been observed alongside an increase in COVID-19 vaccinations, highlighting the need for a thoughtful approach to these occurrences in the clinical setting.
- - A case involving a woman in her 50s who developed symptoms of myopericarditis after receiving the AstraZeneca vaccine was diagnosed with an infected right atrial thrombus, leading to treatment with antibiotics and anticoagulation.
- - This case underscores the necessity for multi-modal imaging and regular follow-up assessments in diagnosing and managing vaccine-related myopericarditis, along with considering additional procedures like endomyocardial biopsy for improved accuracy.
Inflammatory environments induce the generation of dysfunctional IFNγT-betFOXP3 Th1-like Tregs, which show defective function and are found in autoimmune conditions including multiple sclerosis (MS). The pathways that control the generation of Th1-like Tregs are not well understood. Sphingosine-1-phosphate (S1P) signalling molecules are upregulated in Th1-like Tregs, and in vivo S1P inhibition with Fingolimod (FTY720) inhibits the expression of genes responsible for Treg plasticity in MS patients.
View Article and Find Full Text PDFBackground: Patients with heart failure and iron deficiency have diverse causes for hospitalization and death that might be affected by iron repletion.
Objectives: The purpose of this study was to explore causes of hospitalizations and deaths in a randomized trial (IRONMAN) of heart failure comparing intravenous ferric derisomaltose (FDI) (n = 568) and usual care (n = 569).
Methods: Patients with heart failure, left ventricular ejection fraction ≤45%, and either transferrin saturation <20% or serum ferritin <100 μg/L were enrolled.