Publications by authors named "A Akshatha"

As one of 17 clinical sites of the Environmental influences on Child Health Outcomes (ECHO) IDeA States Pediatric Clinical Trials Network (ISPCTN), the Hawai'i IDeA Center for Pediatric and Adolescent Clinical Trials (HIPACT) was established in 2016 to participate in community-valued and scientifically-valid multi-center pediatric clinical trials to improve health and well-being of diverse multi-ethnic populations of Hawai'i. Hawai'i is home to large populations of diverse rural and underserved populations, including indigenous Hawaiian communities and immigrant populations of Pacific Islanders and Asians. Many of these communities experience significant health disparities, made worse by their geographic isolation and many socio-economic factors.

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Article Synopsis
  • The incidence of neonatal opioid withdrawal syndrome (NOWS) has significantly increased over the past decade, highlighting the need for improved management practices.
  • A survey conducted at 54 medical centers showed high adherence to protocols for NOWS care, with intensive care units (NICUs) generally following standardized practices more consistently than non-ICU settings.
  • The study identifies gaps in management practices between NICUs and non-ICUs, suggesting the need for better training and standardized care plans to improve outcomes in non-ICU environments.
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Purpose Of Review: The article is intended to provide an overview of the most current modalities for the diagnosis and management of pulmonary hypertension in the pediatric population.

Recent Findings: The WHO has recently updated the classification for pulmonary hypertension to include an expanded range of pediatric disease cohorts. We continue to gain knowledge of traditional pulmonary hypertension therapies (phosphodiesterase inhibitors, endothelin-receptor antagonists, and prostanoids) and remain optimistic that new therapeutic modalities [cyclic guanosine monophosphate (cGMP) stimulators, oral prostacyclins, and gene therapy] will lead to improved outcomes in pediatric patients.

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