Publications by authors named "A Aksan"

Background: Preeclampsia is a serious pregnancy complication requiring early detection to improve outcomes. Profilin-1 (PFN1), linked to vascular dysfunction, may serve as a biomarker for diagnosing preeclampsia and predicting adverse neonatal outcomes. The aim of this study was to determine the serum Profilin-1 levels in patients diagnosed with preeclampsia and to investigate its association with disease severity and adverse neonatal outcomes.

View Article and Find Full Text PDF
Article Synopsis
  • - Women experience sleep disturbances during key life stages like adolescence, pregnancy, postpartum, and perimenopause due to hormonal changes and conditions such as PCOS and PMS.
  • - The study reviews the management of women's sleep disorders according to the International Classification of Sleep Disorders-3 (ICSD-3), examining the connection between gynecological diseases and sleep issues.
  • - Findings highlight that these physiological changes can lead to increased sleep disorders, emphasizing the need for gynecologists to recognize and address these issues when women present them during medical consultations.
View Article and Find Full Text PDF
Article Synopsis
  • - This study evaluates the effectiveness of inflammation indexes (like SII and NLR) for diagnosing intrahepatic cholestasis of pregnancy (ICP) by reviewing medical records of 242 patients, including 121 with ICP and 121 healthy controls.
  • - Key findings showed significant differences in immune cell counts and liver enzyme levels between the ICP group and controls, with SII and NLR being notably higher in ICP patients.
  • - The study concludes that these systemic inflammation indices can be cost-effective and rapid diagnostic tools for ICP, suggesting they could improve patient outcomes when integrated into standard clinical practice.
View Article and Find Full Text PDF
Article Synopsis
  • * The research analyzed data from 15 CDQ assessments across 12 countries over 16 years, discovering that comprehensive PPs correlate positively with better HRQoL, while policies focused solely on gluten-free meals aren't as effective on their own.
  • * The study emphasizes the need for enhanced patient education and effective regulation monitoring to support CD patients and improve their overall well-being.
View Article and Find Full Text PDF

Objective: To compare overall survival (OS) and morbidity outcomes in patients with advanced epithelial ovarian/tubal/peritoneal cancer undergoing standard-radical (SR) and ultra-radical (UR) surgical procedures based on NICE classification.

Study Design: This retrospective study analyzed data from 282 patients with 2014 FIGO stage III-IV epithelial ovarian cancer operated on between January 2006 and January 2019. The study compared OS, progression-free survival (PFS), and morbidity between SR and UR surgeries.

View Article and Find Full Text PDF