Publications by authors named "A Akrivaki"

Article Synopsis
  • Siponimod is being studied for its potential to treat active secondary progressive multiple sclerosis (SPMS) in a year-long clinical trial involving 50 patients.
  • Over the 12-month follow-up, significant improvements were seen, including reductions in annual relapse rates, the number of gadolinium-enhanced lesions, and fatigue levels.
  • The treatment successfully maintained stable cognitive and physical disability statuses, indicating its overall efficacy for SPMS patients, including those with higher initial disability scores.
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Introduction: Symptomatic carotid artery disease (CAD) represents an uncommon but treatable cause of corticobasal syndrome.

Case Report: We present the clinical details and successful management of a previously healthy 77-year-old patient who presented with 1-year cognitive dysfunction, alien limb syndrome, limb kinetic apraxia, and ipsilateral cortical sensory deficit, fulfilling the criteria of the diagnosis of probable corticobasal syndrome. Imaging modalities, including magnetic resonance imaging and time-of-flight magnetic resonance angiography, revealed acute external borderzone infarcts of the right hemisphere due to symptomatic CAD causing near occlusion of the vessel.

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Objectives: Cerebral venous thrombosis is an uncommon, yet life-threatening condition, affecting mainly young and middle-aged individuals. Moreover, it represents an underrecognised etiology of lobar intracerebral hemorrhage (ICH). The clinical course of CVT is variable in the first days after diagnosis and medical complications including pulmonary embolism (PE) may result in early neurological deterioration and death if left untreated.

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Introduction: Vitamin B6 is a water-soluble vitamin that is naturally present in many foods and is accessible in many dietary supplements. The three natural forms are pyridoxine, pyridoxal, and pyridoxamine. Both vitamin B6 deficiency and high B6 intake have been described as risk factors for developing peripheral neuropathy (PN).

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