Structural Organization of Cerebral Basolateral Nucleus of the Amygdaloid Complex in WAG-Rij Rats with Different Genotypes by the TAQ 1A Locus of Dopamine 2 Receptor Gene (DRD2).

Anxiety levels and structural organization of the basolateral nucleus of the amygdaloid complex were analyzed in WAG/Rij rats with genotypes A/A and A/A by DRD2 locus Taq 1A. Association of anxious behavior with A/A genotype and the relationship between the structural organization of the nucleus and polymorphic variants of this locus are detected.

[The Amygdala in mechanisms of alcohol dependence].

In the present review for the first time systematized literature data about reactive changes, of neurons in the basolateral and medial nuclei of the Amygdala which occur in response to acute and chronic exposure of ethanol. Summarized information about the mechanisms of disturbances in glutamatergic-and GABAergic systems of the basolateral nucleus that determining an increased level of anxiety, which is seen as a main motivating factor of desire for alcohol, thus involved to the manifestation of alcohol dependence. Reviewed molecular and genetic aspects of rsearchs involvement of medial nucleus in the mechanisms of alcoholism.

[IMPAIRMENTS OF GLUTAMATERGIC TRANSMISSION IN THE BASOLATERAL NUCLEUS OF THE AMYGDALA IN THE DEVELOPMENT OF ALCOHOL DEPENDENCE].

In this review for the first time systematized literature data about the impairments of glutamatergic transmission in the basolateral nucleus of the Amygdala which leading to increased levels of anxiety. It is known that increased anxiety is seen as a main motivating factor of desire for alcohol, thus involved in the manifestation of alcohol dependence. Reviewed structural-functional alterations in ionotropic and metabotropic glutamate receptors in acute, chronic ethanol exposure and withdrawal.

Structural bases for neurophysiological investigations of amygdaloid complex of the brain.

Amygdala (Am) as a part of limbic system of the brain defines such important functions as adaptive behavior of animals, formation of emotions and memory, regulation of endocrine and visceral functions. We worked out, with the help of mathematic modelling of the pattern recognition theory, principles for organization of neurophysiological and neuromorphological studies of Am nuclei, which take into account the existing heterogeneity of its formations and optimize, to a great extent, the protocol for carrying out of such investigations. The given scheme of studies of Am's structural-functional organization at its highly-informative sections can be used as a guide for precise placement of electrodes', cannulae's and microsensors into particular Am nucleus in the brain with the registration not only the nucleus itself, but also its extensions.

[NEUROENDOCRINE REPRODUCTIVE CENTERS OF CORTICOMEDIAL DIVISION OF THE AMYGDALA].

In this review for the first time systematized available in modern literature data, which characterize the structural and functional organization of the reproductive centers of corticomedial division of the Amygdala. Given information about physiological mechanisms of their involvement in the organization of sexual behavior, regulation of secretion and excretion of gonadotropines, influence on the processes of sexual maturation of organisms. Involvement of Amygdala in functional systems of the brain, which determine reproductive functions, predefined its participation in the processes of sexual differentiation of the brain.