A Comparison of DNA-DNA Hybridization Kinetics in Complex Media on Planar and Nanostructured Electrodes.

A comprehensive investigation into how nanostructures alter real-time DNA hybridization kinetics in both buffer and complex media and under a wide range of probe and target concentrations is currently lacking. In response, we use a real-time, wash-free, and assay to study DNA hybridization kinetics by performing continuous electrochemical measurements in different media. We investigated the differences in hybridization kinetics under three regimes of probe density (low, medium, and high) and over three orders of magnitude of target concentrations (0.

Evaluating the Relation Between Mothers' Depression Level and Their Cochlear Implanted Children's Social Performance.

Since the child's sensorineural hearing loss and its negative consequences, including weak social skills, is one of the most challenging problems for parents and other family members, the main aim of the present study is to investigate if there is any probable relation between the cochlear implanted children's social performance and their mothers' depression level,in this cross-sectional observational analytic research, we implemented the Beck Depression Inventory version- II to evaluate the level of depression in 29 mothers of cochlear implanted children. Also, we assessed their children's social abilities through the Vineland Adaptive Behavior Scale. Finally, the analysis of variance (ANOVA) was carried out to find any probable relation between the mothers' depression level and their children's social performance.

Gas turbine hot sections condition monitoring based on operational thermal dataset.

This paper aimed to monitor the exhaust gas temperature (EGT) from the end of the low-pressure turbine (LPT) of a gas turbine for period of 6 months. To achieve this, 16 thermocouples were strategically placed to gather data at different points in the exhaust system. This comprehensive approach allowed for a detailed analysis of the exhaust gas temperature, which is a critical factor in the health of hot section of gas turbines.

Evaluation of the safety and efficacy of biosimilar recombinant growth hormone in children with growth hormone deficiency: non-inferiority, randomized, parallel, multicentric and Phase III trial.

Objectives: This study is designed in order to compare the efficacy and safety of recombinant human growth hormone (rhGH) with the reference brand.

Methods: According to the inclusion criteria, 85 people in 13 Iranian centers were randomly selected to receive biosimilar Somatropin (Somatin®) (44 people) and reference Somatropin (Norditropin®) (41 people) at a dose of 35 µg/kg/d, seven days/week for 12 months. The primary outcomes included height velocity (HV) was measured during 12 months of treatment.