AP-2 transcription factors regulate ectodermal development, but their roles in epidermal homeostasis in adult skin are unknown. We find that AP-2α is the predominant AP-2 family member in adult epidermis, followed by AP-2β. Through inactivation of AP-2α, AP-2β, or both in keratinocytes, we assessed the effects of a gradient of epidermal AP-2 activity on skin function.
View Article and Find Full Text PDFLung cancer is a deadly disease showing uncontrolled proliferation of malignant cells in the lungs. If the lung cancer is detected in early stages, it can be cured before critical stage. In recent years, new technologies have gained much attention in the healthcare industry however, the unpredictable appearance of tumors, finding their presence, determining its shape, size and high discrepancy in medical images are the challenging tasks.
View Article and Find Full Text PDFToday COVID-19 pandemic articulates high stress on clinical resources around the world. At present, physical and viral tests are slowly emerging, and there is a need for robust pandemic detection that biomedical sensors can aid. The utility of biomedical sensors is correlated with the medical instruments with physiological metrics.
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