Publications by authors named "A Aghaebrahim"
Background And Objectives: Although previous trials have established the efficacy and safety of endovascular thrombectomy (EVT) in large ischemic core strokes, most of them excluded patients with extracranial internal carotid artery (e-ICA) occlusion. We aimed to compare outcomes in patients with e-ICA occlusion and large ischemic core infarcts treated with EVT vs medical management (MM).
Methods: This was a secondary analysis of the SELECT2 trial, a randomized controlled trial conducted at 31 international sites.
Article Synopsis
- This study analyzed decisions regarding decompressive hemicraniectomy (DHC) and early withdrawal of life-sustaining therapy (WLST) in patients with large vessel occlusion (LVO) and large ischemic strokes from the SELECT2 trial.* -
- Among 352 patients, DHC was utilized in 55 patients, and WLST was chosen for 81, showing no significant differences in usage between those receiving endovascular thrombectomy (EVT) and those treated medically.* -
- About 21% of DHC patients were able to walk independently after one year, indicating that DHC did not negatively impact the benefits of thrombectomy, while WLST generally resulted in poor outcomes.*
Background And Objectives: The Woven EndoBridge (WEB) device is a breakthrough in brain aneurysm treatment, widely used for intracranial wide neck and complex aneurysms, especially at bifurcations. Although effective, aneurysm recurrence can occur post-treatment and the impact of clipping angle on the WEB mesh remains unclear. In this study, using a human placenta-based ex-vivo aneurysm model, we simulated the application of aneurysm clipping on WEB-treated aneurysms to elucidate the technical aspects and nuances, particularly the influence of the angle of clip application on WEB collapse.
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- Endovascular thrombectomy (EVT) has proven safe and effective for patients suffering from large core strokes, but the effects of reperfusion quality and procedure details on outcomes are still unclear.
- In the SELECT2 trial, findings indicated that 80% of patients experienced successful reperfusion, which correlates with better clinical outcomes, particularly in those who achieved near-complete reperfusion.
- Longer procedure times negatively impacted patient outcomes, while the method of thrombectomy (aspiration vs stent-retriever) showed no significant differences in reperfusion success or functional recovery.
Article Synopsis
- Steal syndrome occurs when blood flow is redirected through collateral vessels due to an obstruction in an artery, which can lead to conditions like subclavian steal syndrome and double steal phenomenon.
- A case study presented involves an elderly patient suffering from cerebrovascular issues who experienced neurological symptoms while chewing, linked to specific artery blockages discovered via angiography.
- Successful treatment was achieved by performing endovascular revascularization on the affected arteries using a specialized stent, which resolved the patient’s symptoms.