Publications by authors named "A Afzal"

Article Synopsis
  • High-dose methotrexate (MTX) can lead to serious complications like acute kidney injury (AKI), neutropenia, and liver damage, but glucarpidase, an enzyme that breaks down MTX, shows potential benefits.
  • In a study of 708 patients with MTX-AKI across 28 cancer centers, those receiving glucarpidase had a significantly higher chance of kidney recovery and faster recovery times compared to those who did not receive the treatment.
  • Additionally, glucarpidase treatment was associated with lower rates of severe neutropenia and liver enzyme elevation, but there was no notable difference in mortality rates between the two groups.
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The reuse of electro-coagulated sludge as an adsorbent for Cr(VI) ion reduction was investigated in this study. Electro-coagulated sludge was obtained during the removal of citric acid wastewater by the electrocoagulation process. The following parameters were optimized for Cr(VI) reduction: pH (5-7), initial Cr(VI) concentration (10-50 mg/L), contact time (10-45 min), and adsorbent dosage (0.

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Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a leading cause of chronic liver disease with a significant risk of developing hepatocellular carcinoma (HCC). Recent clinical evidence indicates the potential benefits of statins in cancer chemoprevention and therapeutics. However, it is still unclear if these drugs can lower the specific risk of HCC among patients with MASLD.

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Melatonin, a pleiotropic hormone plays a vital role in enhancing livestock performance not only by regulating circadian rhythms but also by exhibiting antioxidant, immunomodulatory, and metabolic regulatory effects that collectively improve resilience, fertility, and productivity. Melatonin's synthesis is predominantly influenced by light exposure, with increased production in darkness; however, factors such as diet and health status further modulate its levels. By helping animals adapt to environmental stressors, melatonin boosts immune responses, mitigates chronic illnesses, and optimizes production efficiency.

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Tunnel field-effect transistors (TFETs) are gaining interest for low-power applications, but challenges like poor drive current, delayed saturation, and ambipolarity can hinder their performance. This work proposes a dopingless heterojunction TFET (DL-HTDET) utilizing advanced materials, all based on phosphorus, to address these issues. Our approach involves a comprehensive and accurate analysis of the DL-HTDET's behavior.

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