Publications by authors named "A Afiani"

Article Synopsis
  • Severe uncontrolled secondary hyperparathyroidism and a history of kidney transplantation increase the risk of fractures in hemodialyzed patients, and those returning to dialysis after transplant failure face greater health challenges than transplant-naive patients.
  • A study comparing 29 transplant failure patients to 58 transplant-naive patients showed that while initial parathyroid hormone and vitamin D levels were similar, transplant failure patients had significantly higher parathyroid hormone levels and rates of uncontrolled secondary hyperparathyroidism after one year of dialysis.
  • The findings indicate that younger patients with transplant failures are particularly at risk for developing severe secondary hyperparathyroidism, highlighting the need for close monitoring and management in this population.
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In contrast to Staphylococcus aureus intermittent nasal carriers, persistent ones have the highest risk of infection. This study reports the usefulness of a simple nasal sampling algorithm to identify the S. aureus nasal carriage state of hemodialysis patients (HPs) and their subsequent risk of infection.

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For the individual patient with primary IgA nephropathy (IgAN), it remains a challenge to predict long-term outcomes for patients receiving standard treatment. We studied a prospective cohort of 332 patients with biopsy-proven IgAN patients followed over an average of 13 years. We calculated an absolute renal risk (ARR) of dialysis or death by counting the number of risk factors present at diagnosis: hypertension, proteinuria ≥1 g/d, and severe pathologic lesions (global optical score, ≥8).

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Occurrence of cancer after renal transplantation remains a major problem, and the second cause of death. We performed a retrospective analysis of first cancer, first skin cancer, and first organ cancer (including posttransplant lymphoproliferative disease [PTLD]) among 1265 cases from 1979 to 2006. The occurrence of cancer was clearly a time-dependent event justifiying the use of Kaplan-Meier survival and Cox regression methods.

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Primary IgA nephropathy (IgAN) is the most frequent type of primary glomerulonephritis worldwide. The characteristic presentation is gross hematuria at the time of an infectious episode. A renal biopsy still is mandatory for the diagnosis.

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