Publications by authors named "A Adisa"

Ameloblastoma (AM) is a benign but locally infiltrative epithelial odontogenic neoplasm of the jawbones that may reach grotesque proportions and be highly recurrent if inadequately removed. The BRAF mutation has been demonstrated as a key molecular event in its development; nevertheless, there are many queries about its etiopathogenesis, which are yet to be answered. In this study, we aimed to integrate the results from whole-exome sequencing (WES) and RNA sequencing in AM samples to identify novel candidate genes that may be relevant to its pathogenesis.

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Article Synopsis
  • The terminology used to describe developmental lesions in the oral cavity can be confusing, particularly in distinguishing between developmental malformations and neoplasia, especially in odontogenic tumors.
  • The report discusses the definitions of malformations and neoplasia, highlighting their significance within the context of odontogenic tumors.
  • Understanding these concepts is crucial for accurately classifying and treating mixed odontogenic lesions.
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Background: Hemorrhoidectomy is considered as the most effective approach for patients with grade III and grade IV hemorrhoids; the operative procedure may be associated with significant postoperative pain and other complications. Several surgical techniques and devices have been developed to overcome these postoperative problems.

Objective: To compare perioperative and postoperative outcomes of hemorrhoidectomy performed with the LigaSure and the conventional Milligan-Morgan hemorrhoidectomy among Nigerian patients with symptomatic hemorrhoids.

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Background And Objectives: Prospective data on presentation and outcomes of colorectal cancer (CRC) in Nigeria are limited; however, emergency presentation with advanced disease is thought common.

Methods: Consecutive CRC patients presenting at six sites over 6 years were included. Risk factors for emergency presentation were evaluated using logistic regression methods.

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Article Synopsis
  • In Nigeria, gastric cancer ranks as the 10th most common and 9th most deadly cancer, but there is limited data available to fully understand it.
  • A study evaluated 138 patients diagnosed with gastric cancer over 15 years, finding that most patients presented with significant weight loss and anorexia, and many had advanced disease.
  • Most patients received some form of treatment, with nearly half undergoing both chemotherapy and surgery, though over 50% were deceased by the time of follow-up, highlighting the need for improved data quality and timely interventions.
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