Publications by authors named "A Adegoke"

Background: Bone fractures remain a significant global public health issue despite preventive measures, leading to substantial health and economic consequences. Effective treatment options are difficult to access in most sub-Saharan African countries, leading to reliance on unqualified practitioners and resulting in serious complications that worsen poverty. In Nigeria, the main challenge is the need for out-of-pocket payment for healthcare, which is the primary method of health financing.

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  • * Researchers collected and analyzed 421 ticks from various migratory songbird species, identifying key microbial communities and several pathogens present in those ticks.
  • * Findings reveal that specific microbial interactions among ticks could shape pathogen dynamics, highlighting "hotspots" where migrating birds may contribute to the spread of ticks and their associated diseases over long distances.
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  • - This study explored how leaf extracts could help improve symptoms of polycystic ovary syndrome (PCOS) in Wistar rats induced by letrozole.
  • - Treatment with leaf extracts significantly improved hormonal balance and regularity of the estrus cycle, and showed a positive effect by reducing testosterone and increasing estradiol levels.
  • - The extract also normalized several important gene expressions linked to metabolic and hormone regulation, indicating its potential as a promising treatment for PCOS.
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  • * Liposomes were created with a specific ratio of components and attached to a PSA antibody, successfully encapsulating anticancer drugs (doxorubicin and docetaxel) alongside plant extracts.
  • * The study found that heating the liposomes to 39-40 °C activated them, releasing their contents and effectively inhibiting the growth of prostate cancer cell lines (LNCap and DU145) when compared to non-heated conditions.
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