Leukocytoclastic vasculitis due to ruxolitinib treatment: A rare adverse effect.

What Is Known And Objective: Primary myelofibrosis (PMF) is characterized by myeloid cell proliferation and prominent bone marrow fibrosis. Ruxolitinib, a selective inhibitor of JAK 1 and 2, significantly reduces constitutional symptoms and spleen size compared with placebo, and has significant clinical benefits in patients with myelofibrosis. The most common haematological side effects are thrombocytopenia and anaemia, and the most common non-haematological side effects are grade 1-2 diarrhoea and pyrexia.

Cytomorphological findings in diagnosis of Warthin tumor.

Background/aim: To define the cytomorphologic findings leading to difficulties in diagnosis of Warthin tumors (WTs).

Materials And Methods: Forty-eight histopathologically diagnosed WT patients who had fine needle aspiration cytology preoperatively were reevaluated for defining the presence or absence of lymphocytes, oncocytic cell layer, oncocytic cell papillae, granular debris background, mucoid background, macrophages, polymorphonuclear cells, mast cells, squamous-like cells, atypical vacuolated cytoplasmic cells, and giant cells.

Results: Forty-seven tumors were in the parotid gland and one in the submandibular gland.

Aggressive squamous cell carcinoma of the renal pelvis.

Squamous cell carcinoma (SCC) of the renal pelvis is a particularly rare tumor that accounts for a minor portion of renal malignancies and is aggressive with an unfavorable prognosis. It is usually diagnosed after surgery and at advanced stages as it does not possess specific clinical and radiological properties. The pathological examination of a 38-year-old female patient who had undergone nephrectomy due to a nonfunctioning right kidney caused by long-standing staghorn calculus revealed moderately differentiated renal pelvis SCC invading the renal parenchyma.

Two-stage multilevel cervical spondylectomy for aneurysmal bone cyst.

Aneurysmal bone cyst is a benign tumor-like bony lesion with a propensity to develop in the pediatric population. It generally involves one vertebral level when localized to the spine. The degree of resection correlates highly with fewer recurrences.