Spiking Neural Networks (SNNs) stand as the third generation of Artificial Neural Networks (ANNs), mirroring the functionality of the mammalian brain more closely than their predecessors. Their computational units, spiking neurons, characterized by Ordinary Differential Equations (ODEs), allow for dynamic system representation, with spikes serving as the medium for asynchronous communication among neurons. Due to their inherent ability to capture input dynamics, SNNs hold great promise for deep networks in Reinforcement Learning (RL) tasks.
View Article and Find Full Text PDFRev Endocr Metab Disord
December 2024
This paper provides a critical overview on GHRH and its deficiency, discussing its multiple roles in both central and peripheral tissues. Genetically engineered mice have been instrumental in elucidating the multifaceted roles of GHRH and GH, each offering unique insights into the physiological and pathological roles of these hormones, although in many of these models dissecting the direct effect of GHRH from the effect of GH is not possible. Key findings highlight the effects of GHRH deficiency on emotional behavior, including anxiety and depression, its impact on memory and learning capabilities, as well as on adipose tissue, immune system, inflammation and pain.
View Article and Find Full Text PDFAntibiotics (Basel)
October 2024
Urinary tract infections (UTIs) are infections that involve the urethra, bladder, and, in much more severe cases, even kidneys. These infections represent one of the most common diseases worldwide. Various pathogens are responsible for this condition, the most common being ().
View Article and Find Full Text PDFEremurus spectabilis is widespread and used primarily for medicinal and culinary purposes. This study aimed to evaluate the chemical composition, antiradical and antioxidant activities, enzyme inhibitory activities, and anti-inflammatory properties of various extracts from the aerial parts of E. spectabilis.
View Article and Find Full Text PDFChronic inflammation is a recognized risk factor for various cancers, including prostate cancer (PCa). We aim to explore the potential protective effects of aged black garlic extract (ABGE) against inflammation-induced prostate damage and its impact on prostate cancer cell lines. We used an ex vivo model of inflammation induced by Escherichia coli lipopolysaccharide (LPS) on C57BL/6 male mouse prostate specimens to investigate the anti-inflammatory properties of ABGE.
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