Publications by authors named "A Abdouh"

The benefit of beta-blockers (BBs) for myocardial infarction (MI) patients with a preserved left ventricular ejection fraction (LVEF) is uncertain. While beneficial for a reduced LVEF, their efficacy with a preserved LVEF, especially with modern revascularization, is unclear. A PRISMA-guided systematic review and meta-analysis utilized PubMed and EMBASE.

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  • Autoimmune connective tissue diseases (CTDs) such as systemic lupus erythematosus (SLE), systemic sclerosis (SSc), and rheumatoid arthritis (RA) significantly impact pregnant women, leading to maternal and fetal complications.
  • A retrospective study analyzed data from over 18 million deliveries and found higher odds of maternal death, acute kidney injury, and severe complications in mothers with CTDs, alongside increased risks of adverse fetal outcomes like stillbirth and preterm labor.
  • The findings highlight the need for specific preconception counseling and management approaches to improve health outcomes for pregnant women with autoimmune CTDs.
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  • Tricuspid regurgitation (TR) is a serious condition linked to long-term health issues, including severe right heart failure, but newer less invasive treatments like transcatheter valve interventions (TTVI) are gaining attention.
  • A study analyzing over 98,000 tricuspid valve procedures from 2011 to 2020 revealed trends in intervention types, showing a rise in TTVI and a decline in traditional surgical options.
  • Findings indicate demographic factors like age and race affect procedure choice and outcomes, with surgical interventions showing higher mortality rates; further research is needed to understand the causes of these evolving trends in treatment results.
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  • The study looked at how well two types of blood thinners, DOACs and warfarin, work for patients with special heart pumps called LVADs.
  • They found that both types of blood thinners had similar effects on serious blood clots, but DOACs caused fewer big and small bleeding problems.
  • The researchers believe DOACs could be a safer option than warfarin for these patients, but more studies are needed to be sure.
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  • * A meta-analysis of 6 randomized controlled trials (RCTs) involving 1,343 patients found that PCBs significantly reduced target lesion revascularization (TLR) and major adverse cardiovascular events (MACEs) compared to BA after 6-12 months.
  • * While PCBs showed better outcomes in TLR and MACEs, there was no significant difference in all-cause mortality, cardiovascular mortality, myocardial infarction, or stent thrombosis between PCBs and
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